A search in pubmed was conducted for relevant articles over the last 10 years, from 2002 to 20. Arsheen chawla from brs nagar said, my motherinlaw was detected with dengue two days ago and we were giving her lot of kiwi, aloe vera juice and juice of. This study was conducted to evaluate the platelet increasing efficacy of carica papaya leaf extract cple in. The antidengue activity of ple in denvinfected thp1 cells was examined by immunoblotting. Jan 29, 2016 in malaysia, the number of reported cases of dengue fever demonstrates an increasing trend. Research also demonstrated its beneficial traditional role in wound healing, and in the treatment of cardiovascular diseases, dengue fever. While the raw form of papaya leaf extracts can be made at home or bought from the market at anywhere between rs 100 and rs 200 per glass, a bottle of tablets costs up to rs 1,000. Pdf leaf juice of carica papaya l a remedy of dengue fever.
Consuming papaya and papaya leaf juice can help increase the platelet count of those suffering from dengue fever. Guidelines in using carica papaya leaf extract for dengue fever patients 1. This juice could prove to be an effective remedy for dengue fever. Dengue fever treatment with carica papaya leaves extracts asian pacific journal of tropical biomedicine, vol. Guidelines in using carica papaya leaf extract for dengue fever. People in rural areas have used papaya leaf, as an alternative to treat dengue and dengue haemorrhagic fever. Carica papaya leaves juice significantly accelerates the rate of increase in platelet count among patients with dengue fever and dengue haemorrhagic fever. Due to the lack of adequate in vivo evidence in dengue disease model, the present study was initiated to screen and identify the cytokines affected by freezedried c. Papaya extract to treat dengue annals of medical and health. Both the dengue virus and the antibodies released by your immune system to combat the infection interact with platelets in your blood and destroy them. In a pilot study conducted in sri lanka on 12 patients suspected to have dengue, papaya leaf was found to cause an increase in platelet count and total white blood cell count. Carica papaya leaf extract is now being widely used as a treatment for dengue. Research claims that papaya leaves protect platelet cell membranes and prevent their rupture.
Treats dengue fever a common remedy that is advised by all to dengue patients is papaya leaf juice. Dengue fever treatment with carica papaya leaves extracts ncbi. Patients who consume the juice from this plant commonly reported a. Doctors unsure but papaya a hit for dengue treatment delhi.
Potential antidengue concoction of carica papaya c. There is no scientific answer to this question, but the use of papaya leaves has grown phenomenally in the capital in the past few weeks as the mosquitoborne disease sees a spurt, claiming at least five lives in the. Apr 09, 2012 papaya leaf extract is a powerful cancer fighter. Yunita f, hanani e and kristianto j 2012 the effect of carica papaya l. Carica papaya leaves extracts increased platelets over 5 days. The study was conducted to investigate the platelet increasing property of carica papaya leaves juice cplj in patients with dengue fever df. Papaya leaf juice does such a good job of cleansing and healing that drinking it. Dengue fever treatment with carica papaya leaves extracts article pdf available in asian pacific journal of tropical biomedicine 14. There are some reports that carica papaya leaf extract may improve the clinical condition of dengue patients. Papaya leaves also contain high amounts of vitamins a, c, e, k, and b and minerals like calcium, magnesium, sodium magnesium and iron. Inhibition of platelet aggregation by the leaf extract of carica. An herbal medicine being investigated to control the mammoth problem of dengue is the extract of the leaves of the papaya plant, carica papaya.
Treatment of dengue by papaya leaves linkedin slideshare. Subenthiran s, choon tc, cheong kc, thayan r, teck mb, muniandy pk, et al. Nov 15, 20 references o dengue fever treatment with carica papaya leaves extracts nisar ahmad, hina fazal, muhammad ayaz, bilal haider abbasi, ijaz mohammad, lubna fazal. A large ampunt of biomedical research has been done on this subject, including three randomised control clinical trials 3,4,5,6,7,8,9,10,11,12. Papaya leaves for speedy rise of platelet count in dengue. It is an acute illness of sudden onset that usually follows a benign course with symptoms such as headache, fever, exhaustion, severe muscle and joint pain, swollen lymph nodes lymphadenopathy, and rash.
While the simple extract of papaya leaves is commonly used, there are some commercial preparations containing papaya leaf extract available in certain countries. Carica papaya belongs to carricaceae family, which has been proven traditionally to treat dengue fever due to its pharmacological properties to increase platelet count. Carica papaya leaf extract is now being widely used as a treatment for dengue fever in many countries 1 and in some with the approval of their health authorities 2. In anyone suffering from fever, headache or body pain, it is advisable to do dengue ns1 antigen test as early as possible. In malaysia, the number of reported cases of dengue fever demonstrates an increasing trend. Dengue fever treatment with carica papaya leaves extracts. Pdf dengue fever treatment with carica papaya leaves. Nam dang and colleagues in japan has documented papayas powerful anticancer properties and impact against numerous labgrown tumors and without the negative consequences of chemotherapy. Papaya leaf juice contains acetogenin that may be used to prevent many dangerous diseases, including malaria, dengue, and cancer. Being a viral disease, there is no specific drug available for treatment.
Over 2,000 dengue cases were reported in tamil nadu this year. All participants were randomised into two groups, study group and control group. Jun 21, 2017 to conclude, theres good enough evidence to show the beneficial effects of papaya juice in the treatment of dengue. Guidelines in using carica papaya leaf extract for dengue. Guidelines in using carica papaya leaf extract for dengue fever patients. Patients who consume the juice from this plant commonly reported a reduction of dengue fever.
Sanath hettige, who conducted the research on 70 dengue fever. Traditionally, different parts of the papaya plant are used in the treatment of various ailments such as asthma, ulcers, eczema, diabetes, helminth infections and fever nguyen et al. However, during the critical phase of dengue fever, the platelet count will decrease due to the blood vessel rupturing. Antiinflammatory and immunomodulatory properties of. A compound in the juice is known to help with blood clotting and can. Plants 2 573578 9 siddique o, sundus a and ibrahim m f 2014 effects of papaya leaves on thrombocyte counts in denguea case report j pak med assoc. Carica papaya leaf extract papaya leaf has been shown in several clinical studies to be an effective treatment for dengue fever.
The keywords used for the search included dengue treatment, dengue herbal treatment, dengue papaya leaf extract, dengue c. While there is no specific cure to the disease, a popular natural remedy for dengue is papaya leaf. A study conducted by university of florida researchers dr. Feb 08, 2015 papaya use in dengue recently, crude formulations of papaya leaf have been successfully employed in folk medicine in malaysia, indonesia, nepal, india and pakistan for the treatment of dengue infections with hemorrhagic manifestations 10 papaya leaves extract capsules on platelets count and hematocrit level in dengue fever patients. However, the effect of cplj treatment on other parameters that could contribute to dengue pathogenesis such as nonstructural protein 1 ns1 production and viremia level have never been highlighted in any clinical and in vivo studies. Papaya use in dengue recently, crude formulations of papaya leaf have been successfully employed in folk medicine in malaysia, indonesia, nepal, india and pakistan for the treatment of dengue infections with hemorrhagic manifestations 10 papaya leaves extract capsules on platelets count and hematocrit level in dengue fever patients. They believe this plants leaves can increase the platelet level of dengue patients. First dengue vaccine approved by who after twenty years of clinical studies. Here is a round up of some benefits you can reap of papaya leaf juice 1.
Plants 2 573578 9 siddique o, sundus a and ibrahim m f 2014 effects of papaya leaves on thrombocyte counts in dengue a case report j pak med assoc. Feb 16, 2015 carica papaya leaves extracts treatment for dengue fever malay language. Salutary effects of carica papaya leaf extract in dengue fever patientsa pilot study. There is limited study on the use of cam among patients with dengue fever. However, no specific treatment is available for dengue fever induced thrombocytopenia. Micro labs launches pill made from papaya leaf extract to. Pdf dengue fever treatment with carica papaya leaves extracts hina fazal academia. There is no scientific answer to this question, but the use of papaya leaves has grown phenomenally in the capital in the past few weeks as the mosquitoborne disease sees a spurt, claiming at least five lives in the national capital. Carica papaya leaves have been used for traditional treatment of dengue fever and have been reported to exhibit an immunomodulatory activity by affecting the level of cytokine production in vitro and in vivo. Dengue disease is characterized by a marked decrease in platelet count, which is life threatening. Sep 30, 2015 over 2,000 dengue cases were reported in tamil nadu this year. Carica papaya cp leaf extract has recently gained interest in the treatment of dengue, particularly in social media networks, and has shown increasing offlabel use in the disease.
This supports the immune system and naturally fights viral and bacterial invaders in the body. Carica papaya leaves juice significantly accelerates the. Have papaya salad, or have a glass of fresh papaya juice with a. Carica papaya leaves extracts treatment for dengue fever malay language. Carica papaya leaves juice significantly accelerates the rate. To conclude, theres good enough evidence to show the beneficial effects of papaya juice in the treatment of dengue. Due to the lack of adequate in vivo evidence in dengue disease model, the present study was initiated to screen and identify the cytokines affected by freeze. For the treatment of dengue fever the extract was prepared in water. The presence of fever, itchy rash, and headache the dengue.
Complementary alternative medicine use among patients with. Dengue fever is a disease caused by a family of viruses transmitted by infected mosquitoes. Pdf the main objective of the current study is to investigate the potential of carica papaya leaves extracts against dengue fever in 45 year. The main objective of the current study is to investigate the potential of carica papaya leaves extracts against dengue fever in 45 year old patient bitten by carrier mosquitoes. Jul 12, 2018 while there is no specific cure to the disease, a popular natural remedy for dengue is papaya leaf. In some parts of asia, the young leaves of the papaya are steamed and eaten like spinach. Quinine, for instance, was discovered from the cinchona tree. Traditional aboriginal preparation alters the chemical. The purpose f the study is to explore the prospective use of carica papaya leaves extracts for dengue fever that is a painful, debilitating mosquitoborne disease caused by dengue viruses. Salutary effects of carica papaya leaf extract in dengue fever patients a pilot study. Approximately half the patients received the juice, for 3 consecutive days while the others remained as controls and. Papaya leaf juice has for a long time been used in some areas of india and south east asia as a treatment for dengue fever.
Since dengue fever has no vaccine or antiviral treatment available, it has become a burden. Antiinflammatory and immunomodulatory properties of carica. Apr 17, 20 ahmad n, fazal h, ayaz m, abbasi bh, mohammad i, fazal l 2011 dengue fever treatment with carica papaya leaves extracts. Aug 31, 2018 papaya leaves also contain high amounts of vitamins a, c, e, k, and b and minerals like calcium, magnesium, sodium magnesium and iron. The secondary metabolite of plants origin makes up a vast repository of compounds with a wide range of biological. Papaya leaf juice for increasing blood platelets and fight cancer. The worst symptoms of the illness typically last one to two weeks, and most patients will fully recover within several additional weeks. Therefore, the main objectives of this study were to reduce the bitterness of carica papaya extract by. Pdf dengue fever treatment with carica papaya leaves extracts.
The management of dengue virus infection is essentially supportive and symptomatic and no specific treatment is available for increasing the fallen platelets, which have a significant role in causing the mortality of dengue patient. Taking at the launch here, senior medical advisor of micro labs dr prabhu said people made papaya leaf extract at home to treat dengue. The effect of freezedried carica papaya leaf juice treatment. Ahmad n, fazal h, ayaz m, abbasi bh, mohammad i, fazal l 2011 dengue fever treatment with carica papaya leaves extracts. Use papaya plant in the following ways to cure dengue. In addition to this, papaya leaves have also shown to have rich antimalarial properties, too. Complementary and alternative medicine cam has become one of the good alternatives to treat the patients with dengue fever.
Effectiveness of dried carica papaya seeds against human. Carica papaya leaf juice cplj was well known for its thrombocytosis activity in rodents and dengue patients. Evaluation of antidengue activity of carica papaya. Dengue fever symptoms, causes, contagious, rash, prevention. An open labeled randomized controlled trial was carried out on 228 patients with df and dengue haemorrhagic fever dhf. Pdf proliferative activity of saponinreducing carica. Saponin bitterness reduction of carica papaya leaf extracts. It is an ancient home remedy, being followed for ages. References o dengue fever treatment with carica papaya leaves extracts nisar ahmad, hina fazal, muhammad ayaz, bilal haider abbasi, ijaz mohammad, lubna fazal. An array of studies have been reported on the use of c. Sep 24, 2018 carica papaya leaf extract papaya leaf has been shown in several clinical studies to be an effective treatment for dengue fever. Effect of carica papaya leaf extract capsule on platelet. A compound in the juice is known to help with blood clotting and can restrict the internal bleeding caused by the disease. Role of papaya in dengue fever, an evidence based answere.
Papaya leaf juice for increasing blood platelets and fight. In the present study, we investigated the antiviral activity of an aqueous extract of carica papaya leaves ple against dengue virus denv and its effect on platelet augmentation. Carica papaya cp leaf extract has recently gained interest in the treatment of dengue, particularly in social media networks, and has shown. Research has also found papaya leaf extracts to be helpful in dealing with dengue.
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